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Clobetasol Propionate Powder

Clobetasol Propionate Powder

Product Details:

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Product Description

Product details

Product name

Clobetasol propionate

CAS No.

25122-46-7

Density

1.2g/cm3

Molecular Formula

C25H32ClFO5

Flash Point(C)

297.9+/-30.1C

Molecular Weight

466.97

Refractive index

1.582

Specification

Ref Standard

USP38

Items

Requirements

Results

Assay(HPLC,basis on drying)

97.0%102.0%

99.8%

Appearance

White or almost white crystalline powder

Complies

Solubility

Practically insoluble in water,slightly soluble in benzene and diethyl ether,sparingly soluble ethanol,soluble in acetone and in dimethyl sulfoxide,in chloroform,in methanol and in dioxane

Complies

Identification(IR)

Commplies with the standard

Complies

Specific Rotation

+98-+104

+101.6

Melting Point

about 196C

194.0C-196.0C

Residue on Ignition

0.1%

0.05%

Loss on Drying

2.0%

0.31%

Heavy Metals

20ppm

Complies

Related Substances(HPLC)

single impurity

N.m.t 1.0%

0.18%

sum impurity

N.m.t 2.5%

0.32%

Organic Volatile Impurities

THF

720ppm

Complies

Methanol

3000ppm

Complies

DMF

880ppm

Complies

Pyridine

200ppm

Complies

Dichloromethane

600ppm

Complies

Ethanol

5000ppm

Complies

Acetone

5000ppm

Complies

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